Kariofyllis has conducted his master’s degree entitled Molecular pharmacology, Biopharmaceutics and Biomolecular analysis at the University of Patras, Greece. His scientific interests are mainly focused on Personalized medicine using newly developed technologies targeting human genetic disease. In the last three years, Kariofyllis has successfully trained and worked in prestigious Universities and Research Institutes such as the Centre for Genomic Regulation (CRG), Barcelona, Spain, and the King’s College London (KCL), London, United Kingdom, strengthening, even more, his knowledge and skills in the field of Biomedical Science. Kariofyllis considers science his life’s call, setting high expectations and goals with a clear vision to become a distinguished scientist.
Secondment 1: Develop and test relevant panels for preemptive pharmacogenomics: Slovenian -specific PGx panel with DNA from 600 healthy controls
Secondment 2: Validation and translation to the clinic of preemptive pharmacogenomic testing for Personalised Medicine
Secondment 3: Application of semantic data integration strategies
Standardization of disease and population-specific genotyping panel for preemptive pharmacogenomics: Towards population pharmacogenomics
Kariofyllis will advance the existing knowledge and challenges by developing population-specific genotyping panels for preemptive pharmacogenomics, especially for developing European countries, and to define disease-specific pharmacogenomic panels (e.g. cardiovascular diseases, cancer, neuropsychiatric disorders, etc). These panels will be accompanied by a dedicated web-based translational tool to retrieve, in a dynamic manner from regulators’ guidelines and make them available to physicians for optimizing drug prescriptions for patients based on their pharmacogenomic testing results. This project will adopt a truly multidisciplinary approach, including genome informatics, artificial intelligence, and machine learning. Last but not least, an economic evaluation will also be performed to determine the cost-effectiveness of these panels towards reimbursement of these assays and the reduction of the overall healthcare costs.
The general scientific interest and topics of Kariofyllis include Population Genetics and Genomics, Pharmacogenomics, Health Economics with an emphasis on human disease and novel strategies leading to the identification, understanding, diagnosis, and treatment.
He is passionate about photography and nature considering himself a dedicated traveler. Curiosity about everything is also one of his main interests that reflects with a creative manner into his scientific achievements.