I am a PhD candidate at the Erasmus Medical Center (Erasmus MC) in Rotterdam, Netherlands. I completed my master in the field of Genetics at the University of Maragheh, Iran in 2018. I worked on my master thesis at the Immunology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran. The focus of my thesis was on the combination therapy with miR-34a and doxorubicin in Acute T-cell Lymphoblastic Leukemia (T-ALL). My research interest lie in the area of cancer research and cancer treatment. I have collaborated actively with other researchers in the field of cancer and we have published some articles in this regard. Working in this field and participating in related national/international conferences and workshops and collaborating with other researchers made me more interested in continuing my work on cancer research.
Department of Pathology, Erasmus MC, Rotterdam, Netherlands
Supervisors: Johan M. Kros. MD. PhD; Peter van der Spek. PhD
Secondment 1 : Utilizing cyber technologies for multi-omics & data integration
Secondment 2 : Pattern discovery from NGS mutation to multi-source data
Multi-omics integrative analysis to develop personalized medical approaches: Factors to predict the risk of developing brain metastases of common cancers especially Melanoma
The main aim of this project is to develop a patient stratification strategy based on multi-omics data bases and a tool that enables a reliable classification of clinically relevant disease subtypes via advanced pattern recognition, that can be readily translated to the clinic. In this case, we will study the impact of Biomics on the immune system in the development of cancers. We will focus specifically on melanoma. To achieve this goal, we will analyze available data and will validate findings using public databases. In addition, we will study immune pathways on melanoma development in the tumor specimens of two melanoma cohorts present in our laboratory.
My general research interest include identifying novel strategies or therapeutic options such as identifying genes or pathways that can be translated into innovative targeted therapies in cancer treatment.
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